Prof. Swasti TIWARI, Ph.D.
Dr. Swasti Tiwari is Professor and Head of the Department of Molecular Medicine & Biotechnology at Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGI), a tertiary care hospital in the state of Uttar Pradesh, India. Dr. Tiwari is also an adjunct faculty at the Georgetown University Department of Medicine, Washington DC. USA. She received her post-doctoral training from the National Institute of Health, USA. Dr. Tiwari has received many research grants and awards during her research career, including the prestigious Ramalingaswami national fellowship from the Department of Biotechnology, Government of India. Dr. Tiwari initiated translational research programs on biological-nanovesicles at SGPGI with the vision to improve healthcare through the discovery of molecular predictors of diseases. Her research team has discovered and optimized a nanovesicles-based tool for predicting kidney injury. Work from her laboratory provided the first unequivocal mechanism for the direct effect of insulin on nitric oxide production in the kidney and have demonstrated a significant role of the renal insulin receptor in whole-body glucose metabolism and hypertension. Dr. Tiwari has taken several initiatives to launch investigations to assess high-risk pregnancies and cervical cancer. At present, her laboratory is also developing novel tools for placental health analysis. In response to the COVID-19 pandemic, her laboratory has developed an RNA based technology for COVID-19 testing.
1. Rajak S, Hussain Y, Singh K, Tiwari S, Ahmad B, Bharti S, Prakash P. Cellular Fibronectin Containing Extra Domain A Causes Insulin Resistance via Toll-like Receptor 4. Scientific Reports (Nature publishing)- Accepted on May 7th, 2020.
2. Kumari M, Mohan A, Singh S, Ecelbarger CA, Gupta A, Prasad, N., and Tiwari S*. MiR-451 loaded exosomes are released by the renal cells in response to injury and associated with reduced kidney function in human. Frontiers in Physiology-renal 2020 Apr 8;11:234. doi: 10.3389/fphys.2020.00234
3. Sharma R, Kumari M, Prakash P, Gupta S, and Tiwari S* Phosphoenolpyruvatecarboxykinase in urine exosomes reflect impairment in renal gluconeogenesis in earlyinsulin resistance and diabetes accepted on January 29, 2020 in American Journal of Physiology-renal (AJP-renal). 2020 Mar 1;318(3):F720-F731. doi: 10.1152/ajprenal.00507.2019.
4. Godbole NM, Sinha RA, Tiwari S, Pawar SD, Dhole TN. Analysis of influenza virus-induced perturbation in autophagic flux and its modulation during Vitamin D3 mediated anti-apoptotic signaling. Virus Res. 2020 Jun;282:197936. doi: 10.1016/j.virusres.2020.
Office: +91 522 2495642
Prof. Swasti Tiwari
Head, Department of Molecular Medicine and Biotechnology
4th Floor, PMSSY Building,
Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS)
Lucknow-226024, U.P., India
Office number: 0522-2495642, 0522-2495641